San Francisco 49ers tight end George Kittle dropped an interesting take during the "Up & Adams" show on Wednesday.

With Greenlaw’s contract now expired, his role as a key piece of the 49ers’ defense over the years remains undeniable. Bosa ...

The Philadelphia Eagles dominated the Washington Commanders, and the Kansas City Chiefs sneaked past the Buffalo Bills to book a Super Bowl rematch in New Orleans on Feb.

Nick Bosa spoke exclusively to NBC Sports Bay Area’s Jennifer Lee Chan about San Francisco re-hiring Robert Saleh and where the defensive coordinator stands on re-signing Dre Greenlaw.

Robert Saleh cannot personally create turnovers, rush the passer or stop the run. His return as the 49ers’ D-coordinator is no guarantee of success.

Coach Kyle Shanahan has cycled through DeMeco Ryans ... If the 49ers can get maximum performance from Nick Bosa and Fred Warner, another step up from cornerback Deommodore Lenoir and steady ...

The San Francisco 49ers might have pulled off the coup of this year’s coaching cycle, bringing back Robert Saleh to ...

The 49ers have been trying to find a pass rusher to play opposite Nick Bosa for several seasons, and Myles Garrett would be a ...

The San Francisco 49ers should pursue Los Angeles Chargers' impending free-agent edge rusher Khalil Mack to help bolster ...