The basic building blocks of chromatin are nucleosomes, each of which is composed of 146 bp of DNA wrapped around a histone octamer that consists of two copies each of H2A, H2B, H3 and H4.

We're officially launching our Centre for Epigenetics! To mark the occasion, we are organising a one-day conference at QMUL inviting external speakers at different career stages. The scientific ...

The best cloud storage for photos keeps your precious memories safe and lets you manage your collection from anywhere. With photos and videos eating up more space, storing them in the cloud makes ...

"Hopefully another 1,900 people there the next time," he said. Send your photos to [email protected]. Please ensure you adhere to the BBC's rules on photography that can be found here.

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In depth understanding of molecular methods used for addressing epigenetic phenomena in basic research and ... analysis of modified bases in DNA and RNA and histone modifications, high-throughput ...

We further uncover roles for upstream kinases controlling Histone H3 phosphorylation in mediating fascin-dependent nuclear-DNA tethering and in controlling subsequent apoptotic responses. Our findings ...

In recent years, epigenetics has been recognized as an important contributor on tumor progression. Epigenetic changes in cancer include chromatin remodeling, DNA methylation and histone modifications ...

Phosphorylation of this histone at serine 139 (γ-H2AX) is an early cellular response to ionizing radiation and is used as a measure of DSBs (Pilch et al., 2003). Overall, better understanding of the ...

Here, we reveal that HCMV latency in human CD34 + HSC reflects the recruitment on the viral genome of KAP1, a master co-repressor, together with HP1 and the SETDB1 histone methyltransferase ...

Females of the pair-bonded rodent species become attached to their lifelong mates following histone modifications near oxytocin and vasopressin receptor genes. “It’s the first time anyone’s shown any ...