Although the conserved amino acids in the HKD motifs may have dual roles in both the catalytic reaction and the interdomain association, it is unknown whether the hydrophobic amino acids present ...

Proteins can further fold and assemble into complex structures, such as α-helices and β-sheets, which are stabilized by various interactions, including hydrogen bonds, disulfide bridges, and ...

By swapping hydrophobic amino acids for structurally similar hydrophilic ones, the researchers transform hydrophobic transmembrane receptors into water-soluble proteins that don’t need ...

Each amino acid within this polypeptide chain has a different property. For example, glycine is highly hydrophobic, whilst arginine is very hydrophilic. These properties dictate the three ...