Parkinson’s disease doesn’t move in a straight line, so it can be hard to know what’s coming next. Learn why it’s so hard to predict and how its symptoms may change over time.

A person with Shy-Drager syndrome has symptoms of Parkinson's (Parkinsonism), extremely low blood pressure that worsens upon standing, bladder problems, severe constipation, and decreased sweating ...

Parkinson’s disease is a multisystem neurodegenerative disorder ... Breeze RE, et al. Transplantation of embryonic dopamine neurons for severe Parkinson’s disease. N Engl J Med 2001;344:710 ...

The discovery began when an Omani family, whose two daughters developed severe Parkinsonism at a young age, sought answers from their neurologist, Prof. Ramachandiran Nandhagopal and geneticist Dr ...