During the pathogenesis of Parkinson’s disease (PD), α-synuclein pathology may originate in peripheral organs and spread to the CNS. Using human tissue samples and multiple approaches in mouse ...

Understanding the pathogenesis of LID has contributed ... of dyskinesia as a motor complication in the course of Parkinson's disease (PD) includes a spectrum of involuntary movements schematically ...

According to DelveInsight’s epidemiology model, the total diagnosed prevalent cases of Parkinson’s disease were approximately ...

Clinical diagnosis of Parkinson's disease (PD) could be performed in ... and serotoninergic systems has been implicated in the pathogenesis of depression in PD. They have been associated with ...

Genome-wide association studies (GWASs) have linked genetic variants to neuropsychiatric disorders, but their regulatory roles in non-coding regions remain largely unclear. Using the LUHMES neuronal ...

Neuropsychiatric disorders are becoming increasingly prevalent. Given their complex and multifactorial pathogenesis, there is ...

The preliminary data presented in this manuscript seem valuable. The data are currently incomplete and there are numerous technical concerns, some of which may arise from insufficient description of ...

In a groundbreaking development for neurological care, scientists have unveiled an artificial intelligence-powered blood test that has the potential to detect Parkinson’s disease years before ...

People with Parkinson's disease are more likely to develop certain types of dementia. Find out about the causes, symptoms and treatments. Parkinson’s disease is a brain disease that affects around 145 ...

This study identifies 47,350 enhancers active in human neurons during differentiation and links some to genes involved in ...

In a large cohort of patients with autoimmune diseases, treatment with biologic disease-modifying antirheumatic drugs was associated with reduced incidence of Parkinson’s disease, data show.