10). Some have speculated that a physical CSC niche maintained by both paracrine and juxtacrine signalling exists in colon cancers similar to the normal colon stem cell niche supported by ...

This team identifies a novel juxtacrine model by which CDH11 mediates GC cells binding with fibroblasts and activates YAP-TNC signaling in GC cells, which enhances the malignancy of GC cells.