Skene is a census-designated place and unincorporated community located in Bolivar County, Mississippi, United States on Mississippi Highway 446. Skene is approximately 3 miles west of Boyle and approximately 7 miles north of Shaw. Skene was a station on the Boyle and Sunflower branch of the former Yazoo and Mississippi Valley Raiā¦Skene is a census-designated place and unincorporated community located in Bolivar County, Mississippi, United States on Mississippi Highway 446. Skene is approximately 3 miles west of Boyle and approximately 7 miles north of Shaw. Skene was a station on the Boyle and Sunflower branch of the former Yazoo and Mississippi Valley Railroad.