Prevention and Treatment Strategies for Respiratory Syncytial Virus (RSV)
WEBJan 17, 2023 · RSV infects and replicates in the mucosa lining the respiratory tract from the nasopharynx to the distal alveoli. The effects of RSV infection in adults and older children tend to be related to upper respiratory tract pathologies, including rhinorrhea and coryza, symptoms of the common cold.
Mathematical modelling of respiratory syncytial virus (RSV) in low
WEBThe mathematical modelling literature in LMIC has demonstrated the potential effectiveness of RSV vaccines and monoclonal antibodies. This review has demonstrated the importance of accounting for seasonality, social contact rates, immunity from prior infection and maternal antibody transfer.
Modelling respiratory syncytial virus age-specific risk of ...
WEBMay 21, 2024 · We developed a dynamic compartmental model of RSV transmission, stratified by age, prior exposure, and preterm status, and fitted to linked laboratory and hospitalisation data for a population cohort in metropolitan Western Australia.
Risk factors for severe respiratory syncytial virus infection during ...
WEBWe developed a clinical prediction model for the risk of RSV hospital admission during the first year of life, using 16 easily definable and plausibly generalisable predictors. This model had satisfactory predictive performance in validation data from two countries.
Severe respiratory syncytial virus infection in children: burden ...
WEBThe global burden of respiratory syncytial virus (RSV) lower respiratory tract infection (LRTI) in young children is high. The RSV prevention strategies approved in 2023 will be essential to lowering the global disease burden. In this Series paper, we describe clinical presentation, burden of disease, hospital management, emerging therapies, and targeted prevention focusing on developments and ...
Vaccine Efficacy in Adults in a Respiratory Syncytial Virus …
WEBJun 22, 2022 · Immunization with a single dose of RSVpreF vaccine provided protection against symptomatic RSV infection in a viral challenge model.
Epidemic dynamics of respiratory syncytial virus in current and …
WEBDec 4, 2019 · Here, we evaluate the climate drivers of respiratory syncytial virus (RSV), an important determinant of disease in young children. We combine a dataset of county-level observations from the...
Respiratory syncytial virus infection and novel interventions
WEBJul 12, 2023 · In this Review, we provide an overview of RSV interventions in clinical development, highlighting global disease burden, seasonality, pathogenesis, and host and viral factors related to RSV...
Respiratory syncytial virus infections in adults: a narrative review
WEBRespiratory syncytial virus (RSV), an RNA virus spread by droplet infection that affects all ages, is increasingly recognised as an important pathogen in adults, especially among older people living with comorbidities. Distinguishing RSV from other acute viral infections on clinical grounds alone, with sufficient precision to be clinically useful, is not possible.
Respiratory syncytial virus: from pathogenesis to potential …
WEBSep 27, 2021 · Respiratory syncytial virus (RSV) is one of the most important viral pathogens causing respiratory tract infection in infants, the elderly and people with poor immune function, which causes a huge disease burden worldwide every year.
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